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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Nucleoside Antimetabolite/Analog-TX-2552
TX-2552

Chemical Structure : TX-2552

CAS No.: 2446767-14-0

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TX-2552 (TX2552)

货号: PC-28700Not For Human Use, Lab Use Only.

TX-2552 is a coumarin derivative and potent, orally active Tyrosyl-DNA phosphodiesterase 1 (TDP1) with IC50 of 0.62 uM, increases the clastogenic effect of topotecan.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

TX-2552 is a coumarin derivative and potent, orally active Tyrosyl-DNA phosphodiesterase 1 (TDP1) with IC50 of 0.62 uM, increases the clastogenic effect of topotecan.

物理化学性质&存储条件

分子量 392.47
分子式 C25H25FO3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2H-1-Benzopyran-2-one, 7-[[(2E)-3,7-dimethyl-2,6-octadien-1-yl]oxy]-4-(4-fluorophenyl)-

参考文献

1. Zhanataev AK, et al. Bull Exp Biol Med. 2024 May;177(1):30-34.

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