TU-514 | LpxC inhibitor | Probechem Biochemicals

Chemical Structure : TU-514

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TU-514 (TU514)

货号: PC-24471Not For Human Use, Lab Use Only.

TU-514 is a substrate-analog inhibitor of zinc-dependent UDP-3-O-acyl-N-acetylglucosamine deacetylase (LpxC) with Ki of 3.9 uM for E. coli LpxC and IC50 of 7.0 uM (A. aeolicus LpxC)

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生物&药学活性

TU-514 is a substrate-analog inhibitor of zinc-dependent UDP-3-O-acyl-N-acetylglucosamine deacetylase (LpxC) with Ki of 3.9 uM for E. coli LpxC and IC50 of 7.0 uM (A. aeolicus LpxC)

物理化学性质&存储条件

分子量	431.57
分子式	C22H41NO7
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	D-Glucitol, 1,5-anhydro-2-deoxy-2-[2-(hydroxyamino)-2-oxoethyl]-, 3-tetradecanoate

参考文献

1. Coggins BE, et al. Nat Struct Biol. 2003 Aug;10(8):645-51.

2. Jackman JE, et al. J Biol Chem. 2000 Apr 14;275(15):11002-9.

TU-514 (TU514)

生物&药学活性

物理化学性质&存储条件

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TU-514 (TU514)

生物&药学活性

物理化学性质&存储条件

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