TRPV6 inhibitor cis-22a TFA

Chemical Structure : TRPV6 inhibitor cis-22a TFA

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货号: PC-25399Not For Human Use, Lab Use Only.

TRPV6 inhibitor cis-22a TFA is a potent, selective inhibitor of TRPV6 calcium channel with IC50 of 0.32 uM, shows high selectivity against other calcium channels and related TRP targets, selectively reduces cancer cell growth on TRPV6 positive (T47D) breast cancer cells.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

物理化学性质&存储条件

分子量	563.54
分子式	C26H31F6N3O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Piperazine, 1-[cis-4-(3-methylphenyl)cyclohexyl]-4-(3-pyridinyl)-, 2,2,2-trifluoroacetate (1:2)

参考文献

1. Simonin C, et al. Angew. Chem. Int. Ed. Engl. 54, 14748–14752 (2015).

2. Bhardwaj R, et al. Sci Adv. 2020 Nov 27;6(48):eabe1508.