TPO agonist 1 (PAK1-A2)

Chemical Structure : TPO agonist 1

CAS No.: 1033040-23-1

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货号: PC-42122Not For Human Use, Lab Use Only.

TPO agonist 1 (PAK1-A2) is a potent, selective thrombopoietin (TPO) receptor agonist, thrombopoietin mimetic, also is an allosteric PAK1 activator with EC50 of 2.575 uM.

规格	价格	库存
5 mg	￥980	In stock
10 mg	￥1480	In stock
25 mg	￥2580	In stock
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

TPO agonist 1 (PAK1-A2) is a potent, selective thrombopoietin (TPO) receptor agonist, thrombopoietin mimetic, also is an allosteric PAK1 activator with EC50 of 2.575 uM.

物理化学性质&存储条件

分子量	466.4946
分子式	C25H22N8O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	DMSO: ≥ 36 mg/mL
Chemical Name/SMILES	1H-Pyrazole-4,5-dione, 1-(3,4-dimethylphenyl)-3-methyl-, 4-[2-[2-hydroxy-3'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-3-yl]hydrazone]

参考文献

1. Patent WO2008134338A1. 2. Yu He, et al. Cell. 2026 May 28;189(11):3444-3464.e28.