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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Cyclin-dependent Kinase (CDK)-TP-1287
TP-1287

Chemical Structure : TP-1287

CAS No.: 2044686-42-0

TP-1287 (TP1287)

货号: PC-25402Not For Human Use, Lab Use Only.

TP-1287 is a prodrug of Alvocidib (Flavopiridol, HMR-1275), is an orally active CDK9 inhibitor.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

TP-1287 is a prodrug of Alvocidib (Flavopiridol, HMR-1275), is an orally active CDK9 inhibitor.

物理化学性质&存储条件

分子量 481.82
分子式 C21H21ClNO8P
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(2-Chlorophenyl)-5-hydroxy-8-((3S,4R)-3-hydroxy-1-methylpiperidin-4-yl)-4-oxo-4H-chromen-7-yl dihydrogen phosphate

参考文献

1. Tyagi E, et al. Blood, 2018, 132: 3269.

2. Kim W, et al. Cancer Research, 2017, 77(13_Supplement): 5133-5133.

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