TNG-2673 (TNG2673)

Chemical Structure : TNG-2673

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货号: PC-28132Not For Human Use, Lab Use Only.

TNG-2673 is a potent, selective, allosteric inhibitor of Golgi glycosyltransferase MGAT1 with IC50 of 43 nM, inhibits MGAT1 through a UDP-noncompetitive mechanism.

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TNG-2673 is a potent, selective, allosteric inhibitor of Golgi glycosyltransferase MGAT1 with IC50 of 43 nM, inhibits MGAT1 through a UDP-noncompetitive mechanism.

物理化学性质&存储条件

分子量	478.50
分子式	C25H24F2N6O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(3-(aminomethyl)-5-(3,5-dimethyl-4H-1,2,4-triazol-4-yl)phenyl)-2-cyclobutoxy-7,8-difluoroquinoline-4-carboxamide

参考文献

1. Vassallo KM, et al. J Biol Chem. 2026 Sep 12:113551.

TNG-2673 (TNG2673)

生物&药学活性

物理化学性质&存储条件

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TNG-2673 (TNG2673)

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物理化学性质&存储条件

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