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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Cyclin-dependent Kinase (CDK)-TMX-2039
TMX-2039

Chemical Structure : TMX-2039

CAS No.: 2488892-01-7

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TMX-2039 (TMX2039)

货号: PC-21527Not For Human Use, Lab Use Only.

TMX-2039 is a pan-CDK inhibitor with low nanomolar enzymatic IC50s (0.5-50 nM) for both cell cycle CDKs (CDK1, CDK2, CDK4, and CDK6) and transcriptional CDKs (CDK7 and CDK9).

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10 mg ￥980 In stock
25 mg ￥1580 In stock
50 mg ￥2580 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

TMX-2039 is a pan-CDK inhibitor with low nanomolar enzymatic IC50s (0.5-50 nM) for both cell cycle CDKs (CDK1, CDK2, CDK4, and CDK6) and transcriptional CDKs (CDK7 and CDK9).

物理化学性质&存储条件

分子量 487.35
分子式 C17H20BrFN6O3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-((5-bromo-2-((1-(methylsulfonyl)piperidin-4-yl)amino)pyrimidin-4-yl)amino)-6-fluorobenzamide

参考文献

1. Teng M, et al. Angew Chem Int Ed Engl. 2020 Aug 10;59(33):13865-13870.

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