TH1834 | Tip60 inhibitor | Probechem Biochemicals

Chemical Structure : TH1834

CAS No.: 2108830-08-4

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TH1834 (TH-1834, TH 1834)

货号: PC-60498Not For Human Use, Lab Use Only.

TH1834 (TH-1834, TH 1834) is a novel potent specific histone acetyltransferase Tip60 inhibitor.

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10 mg	￥2180	In stock
25 mg	￥3680	In stock
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生物&药学活性

TH1834 (TH-1834, TH 1834) is a novel potent specific histone acetyltransferase Tip60 inhibitor; induces apoptosis in breast cancer cell lines with more cytotoxicity than staurosporine.
TH1834 increases the γH2AX foci in the cancer cell lines PC-3 and DU-145 combined with IR.
TH1834 induces apoptosis and increases unrepaired DNA damage in breast cancer cells.

物理化学性质&存储条件

分子量	568.722
分子式	C33H40N6O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(5-(4-((phenethyl(4-(4-(pyrrolidin-1-ylmethyl)phenoxy)butyl)amino)methyl)phenyl)-2H-tetrazol-2-yl)acetic acid

参考文献

1. Gao C, et al. Sci Rep. 2014 Jun 20;4:5372.

TH1834 (TH-1834, TH 1834)

生物&药学活性

物理化学性质&存储条件

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TH1834 (TH-1834, TH 1834)

生物&药学活性

物理化学性质&存储条件

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