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首页-小分子抑制剂&激动剂-Tyrosine Kinase-DYRK-TBID
TBID

Chemical Structure : TBID

CAS No.: 1639895-85-4

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TBID (tBID)

货号: PC-42167Not For Human Use, Lab Use Only.

tBID is a potent, selective and cell permeable homeodomain-interacting protein kinase 2 (HIPK2) inhibitor with IC50 of 0.33 uM.

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10 mg ￥2980 In stock
25 mg ￥4980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

tBID is a potent, selective and cell permeable homeodomain-interacting protein kinase 2 (HIPK2) inhibitor with IC50 of 0.33 uM.
tBID displays selectivity Gini coefficient 0.592 out of a panel of 76 kinases, and also inhibits HIPK1 and HIPK3 with less efficiently.
tBID the first pharmacological tool to down regulate cellular HIPK2 in cells.

物理化学性质&存储条件

分子量 528.7764
分子式 C11H3Br4N3O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: 26 mg/mL
Chemical Name/SMILES

1H-Isoindole-1,3(2H)-dione, 4,5,6,7-tetrabromo-2-(1H-imidazol-2-yl)-

参考文献

1. Cozza G, et al. PLoS One. 2014 Feb 24;9(2):e89176.

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