TA-01 |CAS:1784751-18-3 Probechem Biochemicals

Chemical Structure : TA-01

CAS No.: 1784751-18-3

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TA-01 (TA01;TA 01)

货号: PC-42058Not For Human Use, Lab Use Only.

TA-01 is a potent inhibitor of Casein Kinase CK1ε, CK1δ and p38α with IC50 of 6.4, 6.8 and 6.7 nM, respectively.

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5 mg	￥1180	In stock
10 mg	￥1780	In stock
25 mg	￥2980	In stock
50 mg	￥4880	In stock
100 mg		Get quote

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生物&药学活性

TA-01 is a potent inhibitor of Casein Kinase CK1ε, CK1δ and p38α with IC50 of 6.4, 6.8 and 6.7 nM, respectively.
TA-01 inhibits the phosphorylation of proteins downstream of p38α MAPK such as MAPKAPK2 and HSP27 during cardiogenesis, and increases ATF-2 and MEF2C during cardiac differentiation.

物理化学性质&存储条件

分子量	351.3246
分子式	C20H12F3N3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Pyridine, 4-[2-(2,6-difluorophenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl]-

参考文献

1. Laco F, et al. J Mol Cell Cardiol. 2015 Mar;80:56-70.

TA-01 (TA01;TA 01)

生物&药学活性

物理化学性质&存储条件

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TA-01 (TA01;TA 01)

生物&药学活性

物理化学性质&存储条件

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