T0080 | FPR1 antagonist | Probechem Biochemicals

Chemical Structure : T0080

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T0080 (T-0080)

货号: PC-25756Not For Human Use, Lab Use Only.

T0080 is a potent, selective, CNS-penetrating formyl peptide receptor 1 (FPR1) antagonist, reduces brain inflammation and neurodegeneration in animal model of multiple sclerosis (MS).

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生物&药学活性

T0080 is a potent, selective, CNS-penetrating formyl peptide receptor 1 (FPR1) antagonist, reduces brain inflammation and neurodegeneration in animal model of multiple sclerosis (MS).

物理化学性质&存储条件

分子量	457.45
分子式	C24H22F3N3O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Pyrrolo[3,4-c]pyrazol-6(2H)-one, 4,5-dihydro-3-(2-hydroxy-5-methylphenyl)-5-(tetrahydro-2H-pyran-4-yl)-4-[4-(trifluoromethyl)phenyl]-

参考文献

1. Li Y, et al. Targeting formyl peptide receptor 1 reduces brain inflammation and neurodegeneration. Science. 2025 Nov 13;390(6774):eadq1177.

T0080 (T-0080)

生物&药学活性

物理化学性质&存储条件

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T0080 (T-0080)

生物&药学活性

物理化学性质&存储条件

参考文献

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