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首页-小分子抑制剂&激动剂-Others-Other Targets-T-10418
T-10418

Chemical Structure : T-10418

CAS No.: 1608784-68-4

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T-10418 (T10418)

货号: PC-22564Not For Human Use, Lab Use Only.

T-10418 is a potent, selective agonist of G protein-coupled receptor G2A (GPR132) with EC50 of 0.82 uM.

规格 价格 库存 数量
5 mg ￥2580 In stock
10 mg ￥3980 In stock
25 mg ￥5980 In stock
50 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

T-10418 is a potent, selective agonist of G protein-coupled receptor G2A (GPR132) with EC50 of 0.82 uM.
T-10418 exhibits higher potency than the reference and natural ligand 9-HODE and high selectivity among G protein-coupled receptors.
T-10418 has favorable activity, a clean selectivity profile, excellent solubility, and high metabolic stability, is a pharmacological tool to investigate the effects of G2A activation.

物理化学性质&存储条件

分子量 376.41
分子式 C22H20N2O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(3-(pyridin-3-ylmethoxy)benzoyl)-D-phenylalanine

参考文献

1. Hernandez-Olmos V, et al. J Med Chem. 2024 Jun 25. doi: 10.1021/acs.jmedchem.3c02164.

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