Stafib-2-CR

Chemical Structure : Stafib-2-CR

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货号: PC-26211Not For Human Use, Lab Use Only.

Stafib-2-CR is highly potent, selective inhibitor of transcription factor STAT5b with IC50 of 26 nM, shows 69-fold selectivity over STAT5a.

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生物&药学活性

Stafib-2-CR is highly potent, selective inhibitor of transcription factor STAT5b with IC50 of 26 nM, shows 69-fold selectivity over STAT5a.
Stafib-2-CR displays 400-2700 fold selectivity against the other STAT proteins.
Stafib-2-CR binds to STAT5b with ITC Kd of 94 nM, fourfold higher affinity than Stafib-2 (Cat# PC-61167).

物理化学性质&存储条件

分子量	670.50
分子式	C30H28N2O12P2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(2-(4-((4-phenoxyphenyl)carbamoyl)phenoxy)acetyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diyl bis(dihydrogen phosphate)

参考文献

1. Münzel T, et al. Chemistry. 2025 Nov 30:e02809.

Stafib-2-CR

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物理化学性质&存储条件

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Stafib-2-CR

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物理化学性质&存储条件

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