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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-Thyroid Hormone Receptor (THR)-Sob-AM2
Sob-AM2

Chemical Structure : Sob-AM2

CAS No.: 2128258-47-7

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Sob-AM2

货号: PC-25536Not For Human Use, Lab Use Only.

Sob-AM2 is the CNS-selective prodrug of thyroid hormone analog sobetirome (Thyromimetic GC-1, QRX-431)), which is a potent T3 mimic that binds to the TH receptors with subtype selectivity for thyroid hormone receptor beta (TRβ) over thyroid hormone receptor alpha (TRα).

规格 价格 库存 数量
5 mg ￥1980 In stock
10 mg ￥3280 In stock
25 mg ￥5480 In stock
50 mg Get quote
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Sob-AM2 is the CNS-selective prodrug of thyroid hormone analog sobetirome (Thyromimetic GC-1, QRX-431)), which is a potent T3 mimic that binds to the TH receptors with subtype selectivity for thyroid hormone receptor beta (TRβ) over thyroid hormone receptor alpha (TRα).

物理化学性质&存储条件

分子量 341.45
分子式 C21H27NO3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-(4-(4-Hydroxy-3-isopropylbenzyl)-3,5-dimethylphenoxy)-N-methylacetamide

参考文献

1. Bárez-López S, et al. Thyroid. 2018 Sep;28(9):1211-1220.

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