Sinomenine

Chemical Structure : Sinomenine

CAS No.: 115-53-7

加入收藏

货号: PC-27621Not For Human Use, Lab Use Only.

规格	价格	库存
100 mg	￥380	In stock
250 mg	￥580	In stock
1 g	￥1280	In stock
5 g		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

Sinomenine is a natural alkaloid with potential anti-fibrotic activity, inhibits the binding of Keap1 to Nrf2, promotes the nuclear accumulation of Nrf2, induces upregulated expressions of Nrf2-dependent antioxidative genes.
Sinomenine regulates macrophage reprogramming via the PI3K-AKT-NF-kappaB pathway to ameliorate osteoarthritis.
Sinomenine regulates the AKT/FOXO3/GLUL pathway to inhibit pulmonary fibroblast-to-myofibroblast transition via alpha7nAChR against rheumatoid arthritis associated interstitial lung disease.
Sinomenine efficiently induces nuclear translocation of Nrf2, and increased in ARE activity in a concentration-dependent manner.

物理化学性质&存储条件

分子量	329.40
分子式	C19H23NO4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(4bR,8aS,9S)-4-Hydroxy-3,7-dimethoxy-11-methyl-9,10-dihydro-5H-9,4b-(epiminoethano)phenanthren-6(8aH)-one

参考文献

1. Guan T, et al. Arch Biochem Biophys. 2024 Mar;753:109928.

2. Zhang L, et al. Tissue Cell. 2026 Jul 9;104(Pt 1):103766.

3. Liu M, et al. Pharmacol Res. 2026 Jul 4;231:108332.

4. Liu L, et al. Int J Immunopharmacol. 1994 Aug;16(8):685-91.

Sinomenine

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Sinomenine

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.