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Salvinorin A

Chemical Structure : Salvinorin A

CAS No.: 83729-01-5

Salvinorin A (Salvinorin)

货号: PC-26942Not For Human Use, Lab Use Only.

Salvinorin A is a potent, selective and high efficacy kappa-opioid receptor (KOR) agonist with Ki value of 4.3 nM.

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2 mg ¥2780 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Salvinorin A is a potent, selective and high efficacy kappa-opioid receptor (KOR) agonist with Ki value of 4.3 nM.
Salvinorin A is a neoclerodane diterpene and active component of S. divinorum.
Salvinorin A has short lasting effects in vivo and limited oral bioavailability, probably due to acetate metabolism.
Salvinorin A profoundly alters consciousness and perception in vivo.

物理化学性质&存储条件

分子量 432.47
分子式 C23H28O8
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-9-acetoxy-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxododecahydro-2H-benzo[f]isochromene-7-carboxylate

参考文献

1. Butelman ER, et al. Front Pharmacol. 2015 Sep 8;6:190.

2. John TF, et al. Eur J Pharmacol. 2006 Sep 18;545(2-3):129-33.

3. Béguin C, et al. J Pharmacol Exp Ther. 2008 Jan;324(1):188-95.

4. Munro TA, et al. J Med Chem. 2005 Jan 27;48(2):345-8.

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