SU5402 | Tyrosine kinase inhibitor | Probechem Biochemicals

Chemical Structure : SU5402

CAS No.: 215543-92-3

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SU5402 (SU-5402, SU 5402)

货号: PC-42567Not For Human Use, Lab Use Only.

SU5402 is a multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGFRβ, respectively.

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10 mg	￥780	In stock
25 mg	￥1280	In stock
50 mg	￥1980	In stock
100 mg		Get quote

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生物&药学活性

SU5402 is a multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGFRβ, respectively.
SU5402 weakly inhibits insulin receptor.
SU5402 specifically inhibits the growth of the t(4;14)-positive MM lines, KMS-11 and OPM-2, reduces cell viability and increases apoptosis.

物理化学性质&存储条件

分子量	296.3205
分子式	C17H16N2O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 30 mg/mL
Chemical Name/SMILES	1H-Pyrrole-3-propanoic acid, 2-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-4-methyl-

参考文献

1. Mohammadi M, et al. Science. 1997 May 9;276(5314):955-60.

2. Udayakumar TS, et al. Int J Cancer. 2001 Jan 15;91(2):187-92.

3. Hoffman MP, et al. Development. 2002 Dec;129(24):5767-78.

4. Grand EK, et al. Leukemia. 2004 May;18(5):962-6.

SU5402 (SU-5402, SU 5402)

生物&药学活性

物理化学性质&存储条件

参考文献

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SU5402 (SU-5402, SU 5402)

生物&药学活性

物理化学性质&存储条件

参考文献

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