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首页-小分子抑制剂&激动剂-Immunology/Inflammation-STING-STING inhibitor diABZI-i
STING inhibitor diABZI-i

Chemical Structure : STING inhibitor diABZI-i

CAS No.: 2305940-34-3

STING inhibitor diABZI-i (STING-IN-6 )

货号: PC-24986Not For Human Use, Lab Use Only.

STING inhibitor diABZI-I (STING-IN-6) is a potent, small molecule inhibitor of STING, inhibits cGAMP-induced IFNβ in PBMCs with IC50 of 49 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

STING inhibitor diABZI-I (STING-IN-6) is a potent, small molecule inhibitor of STING, inhibits cGAMP-induced IFNβ in PBMCs with IC50 of 49 nM.

物理化学性质&存储条件

分子量 869.00
分子式 C46H52N12O6
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(E)-1-((E)-4-((E)-5-carbamoyl-2-((1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)imino)-3-methyl-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-2,3-dimethylbut-2-en-1-yl)-2-((1-ethyl-3-methyl-1H-pyrazole-5-carbonyl)imino)-7-((3-methoxybenzyl)oxy)-3-methyl-2,3-dihydro-1H-benzo[d]imidazole-5-carboxamide

参考文献

1. Xie T, et al. Nat Commun. 2025 Jul 1;16(1):5695.

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