SRT3109 (AZD-5122) | CXCR2 antagonist | Probechem Biochemicals

Chemical Structure : SRT3109

CAS No.: 1204707-71-0

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SRT3109 (SRT-3109, AZD-5122, AZD5122)

货号: PC-28151Not For Human Use, Lab Use Only.

SRT3109 (AZD-5122) is a potent, selective antagonist of CXCR2 with pIC50 of 8.2, significantly reduces pancreatic tissue edema and inflammation infiltration scores.

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25 mg	￥1480	In stock
50 mg	￥2480	In stock
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生物&药学活性

SRT3109 (AZD-5122) is a potent, selective antagonist of CXCR2 with pIC50 of 8.2, significantly reduces pancreatic tissue edema and inflammation infiltration scores.
SRT3109 significantly reduced the mRNA of inflammatory factors IL-1β, TNF-α, and IL-6 in AP pancreatic tissue.

物理化学性质&存储条件

分子量	475.53
分子式	C18H23F2N5O4S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(2-(2,3-difluorobenzylthio)-6-((2R,3R)-3,4-dihydroxybutan-2-ylamino)pyrimidin-4-yl)azetidine-1-sulfonamide

参考文献

1. Patent WO2010007427 A1 2010-01-21.

SRT3109 (SRT-3109, AZD-5122, AZD5122)

生物&药学活性

物理化学性质&存储条件

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SRT3109 (SRT-3109, AZD-5122, AZD5122)

生物&药学活性

物理化学性质&存储条件

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