SRI-29132

Chemical Structure : SRI-29132

加入收藏

货号: PC-24618Not For Human Use, Lab Use Only.

SRI-29132 is a potent, highly selective and brain-permeable LRRK2 inhibitor with IC50 of 146 nM and 75 nM in WT LRRK2 and G2019S-LRRK2 cis-autophosphorylation kinase assays respectively.

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

SRI-29132 is a potent, highly selective and brain-permeable LRRK2 inhibitor with IC50 of 146 nM and 75 nM in WT LRRK2 and G2019S-LRRK2 cis-autophosphorylation kinase assays respectively.

物理化学性质&存储条件

分子量	387.52
分子式	C18H21N5OS2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(piperidin-1-yl)-2-((3-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)thio)butan-1-one

参考文献

1. Liu Z, et al. J Biol Chem. 2014 Nov 21;289(47):32937-51.

2. Moukha-Chafiq O, et al. J Med Chem. 2025 May 12. doi: 10.1021/acs.jmedchem.4c02473.

SRI-29132

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

SRI-29132

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.