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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Adenylate Cyclase-SQ-22536
SQ-22536

Chemical Structure : SQ-22536

CAS No.: 17318-31-9

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SQ-22536 (SQ22536)

货号: PC-42132Not For Human Use, Lab Use Only.

SQ-22536 is a potent, non-competitive Adenylyl Cyclase inhibitor with IC50 of 1.4 uM.

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10 mg ￥780 In stock
25 mg ￥1380 In stock
50 mg ￥2180 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

SQ-22536 is a potent, non-competitive Adenylyl Cyclase inhibitor with IC50 of 1.4 uM.
SQ-22536 abolishes the iloprost-induced elevation in cyclic AMP while having no significant effect on relaxation in isolated guinea-pig aorta.

物理化学性质&存储条件

分子量 205.2165
分子式 C9H11N5O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 29 mg/mL
Chemical Name/SMILES

9H-Purin-6-amine, 9-(tetrahydro-2-furanyl)-

参考文献

1. Fabbri E, et al. J Enzyme Inhib. 1991;5(2):87-98.

2. Hourani SM, et al. Br J Pharmacol. 2001 Jul;133(6):833-40.

3. Turcato S, et al. Br J Pharmacol. 1999 Feb;126(4):845-7.

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