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首页-小分子抑制剂&激动剂-Proteasome/Ubiquitin-Heat Shock Protein (HSP)-SOMCL-16-175
SOMCL-16-175

Chemical Structure : SOMCL-16-175

CAS No.: 1903682-64-3

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SOMCL-16-175

货号: PC-20551Not For Human Use, Lab Use Only.

SOMCL-16-175 is a non-covalent, allosteric modulator targeting Hsp90α’s middle domain (Hsp90M) with binding Kd of 804 uM, inhibits breast cancer cell growth and proliferation.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

SOMCL-16-175 is a non-covalent, allosteric modulator targeting Hsp90α’s middle domain (Hsp90M) with binding Kd of 804 uM, inhibits breast cancer cell growth and proliferation.

物理化学性质&存储条件

分子量 242.10
分子式 C10H9Cl2N3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

ClC1=C(CC2=CN=C(N)N2)C=CC(Cl)=C1

参考文献

1. Zhou C, et al. iScience. 2020 Feb 21;23(2):100857.

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