SNM1A inhibitor 19

Chemical Structure : SNM1A inhibitor 19

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货号: PC-22445Not For Human Use, Lab Use Only.

SNM1A inhibitor 19 is a cell-active small molecule inhibitor of SNM1A DNA repair nuclease with IC50 of 44 uM, sensitises cancer cells to cisplatin and delays resolution of cisplatin-induced DNA damage.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

SNM1A inhibitor 19 is a cell-active small molecule inhibitor of SNM1A DNA repair nuclease with IC50 of 44 uM, sensitises cancer cells to cisplatin and delays resolution of cisplatin-induced DNA damage.

物理化学性质&存储条件

分子量	361.79
分子式	C16H16ClN5O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-2-((6-chloro-2-((furan-2-ylmethyl)amino)quinazolin-4-yl)amino)-N-hydroxypropanamide

参考文献

1. Marcin Bielinski, et al. Chem Sci. 2024 Apr 30;15(21):8227-8241.