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首页-小分子抑制剂&激动剂-Immunology/Inflammation-STING-SN-001
SN-001

Chemical Structure : SN-001

CAS No.: 727699-84-5

SN-001 (SN001, DUN99845, DUN 99845)

货号: PC-38104Not For Human Use, Lab Use Only.

SN-001 (DUN99845) is a small molecule STING inhbitor targeting the cyclic dinucleotide binding pocket, inhibits the activation of the STING signal pathway with IC50 of 3.82 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

SN-001 (DUN99845) is a small molecule STING inhbitor targeting the cyclic dinucleotide binding pocket, inhibits the activation of the STING signal pathway with IC50 of 3.82 uM.

物理化学性质&存储条件

分子量 476.522
分子式 C26H21FN2O4S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-[3-[[(4-Fluorophenyl)sulfonyl]amino]-4-methoxyphenyl][1,1'-biphenyl]-4-carboxamide

参考文献

1. Hong Z, et al. Proc Natl Acad Sci U S A. 2021 Jun 15;118(24):e2105465118.

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