欢迎访问ProbeChem中文网站，英文网站请访问www.probechem.com
    英文 |     中文

产品咨询: sales@probechem.com
订购: order@probechem.com

首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-ATM/ATR-SKLB-197
SKLB-197

Chemical Structure : SKLB-197

CAS No.: 2713577-16-1

加入收藏

SKLB-197 (SKLB197)

货号: PC-72744Not For Human Use, Lab Use Only.

SKLB-197 is a potent and highly selective ATR kinase inhibitor with IC50 of 13 nM.

规格 价格 库存 数量
5 mg ￥1780 In stock
10 mg ￥2780 In stock
25 mg ￥4880 In stock
50 mg Get quote
100 mg Get quote
获取报价单
* 请选择数量再加入购物车
 or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

SKLB-197 is a potent and highly selective ATR kinase inhibitor with IC50 of 13 nM.
SKLB-197 displays very weak or no activity against other a panel of 402 protein kinases.
SKLB-197 exhibited potent antitumor activity against ATM-deficent tumors both in vitro and in vivo, with good pharmacokinetic properties.

物理化学性质&存储条件

分子量 424.508
分子式 C25H24N6O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Quinazoline, 2-(1H-indol-4-yl)-4-[(3R)-3-methyl-4-morpholinyl]-6-(1-methyl-1H-pyrazol-5-yl)-

参考文献

1. Huachao Bin, et al. Eur J Med Chem. 2022 Mar 15;232:114187.

备案号：沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

联系我们 sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

询单

  • *产品名称:
  • *姓名:
  • *邮箱:
  • *公司名称:
  • *询单数量:
  • *国籍:
  • 询单信息: