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首页-小分子抑制剂&激动剂-GPCR-Sigma Receptor-SKF83959 hydrobromide
SKF83959 hydrobromide

Chemical Structure : SKF83959 hydrobromide

CAS No.: 67287-95-0

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SKF83959 hydrobromide (SKF 83959 hydrobromide)

货号: PC-25927Not For Human Use, Lab Use Only.

SKF83959 hydrobromide is a potent and selective dopamine D1-like receptor partial agonist with binding Ki of 1.18, 7.56, 920 and 399 nM for rat D1, D5, D2 and D3 receptors respectively, also is a potent allosteric modulator of Sigma 1 receptor (S1R), shows anti-seizure activities.

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5 mg ￥2180 In stock
10 mg ￥3580 In stock
25 mg ￥5580 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

SKF83959 hydrobromide is a potent and selective dopamine D1-like receptor partial agonist with binding Ki of 1.18, 7.56, 920 and 399 nM for rat D1, D5, D2 and D3 receptors respectively, also is a potent allosteric modulator of Sigma 1 receptor (S1R), shows anti-seizure activities.

物理化学性质&存储条件

分子量 398.73
分子式 C18H21BrClNO2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

6-chloro-3-methyl-1-(m-tolyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol hydrobromide

参考文献

1. Panchalingam S, et al. Neuropharmacology. 2001 May;40(6):826-37.

2. Jin LQ, et al. J Neurochem. 2003 Apr;85(2):378-86.

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