Chemical Structure : SKF-91488
CAS No.: 68941-21-9
货号: PC-27382Not For Human Use, Lab Use Only.
SKF-91488 (Homodimaprit, SKF 91488) is a potent, noncompetitive histamine N-methyltransferase (HNMT) inhibitor with Ki of 0.9 uM, blocks histamine metabolism and increases histamine concentrations, can increase blood pressure and enhance bronchoconstriction.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 mg | ¥780 | In stock | |
| 50 mg | ¥1180 | In stock | |
| 100 mg | ¥1880 | In stock | |
| 250 mg | Get quote |
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SKF-91488 (Homodimaprit, SKF 91488) is a potent, noncompetitive histamine N-methyltransferase (HNMT) inhibitor with Ki of 0.9 uM, blocks histamine metabolism and increases histamine concentrations, can increase blood pressure and enhance bronchoconstriction.
| 分子量 | 248.21 | |
| 分子式 | C7H19Cl2N3S | |
| 外观性状 | Solid | |
| 储存条件 |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
4-(Dimethylamino)butyl carbamimidothioate dihydrochloride |
|
1. Donaldson J, et al. Br J Pharmacol. 1986 Jan;87(1):191-9.
2. Poulakos JJ, et al. J Pharmacol Exp Ther. 1986 Dec;239(3):730-6.
3. Klein MC, et al. J Pharmacol Exp Ther. 1981 Feb;216(2):315-20.
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