SJ-172550 |CAS:431979-47-4 Probechem Biochemicals

Chemical Structure : SJ-172550

CAS No.: 431979-47-4

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SJ-172550 (SJ172550;SJ 172550)

货号: PC-45010Not For Human Use, Lab Use Only.

SJ-172550 (SJ172550) is the first small molecule MDMX inhibitor that reversibly binds the p53-binding pocket of MDMX, disrupts MDMX-p53 interaction with EC50 of 2.3 uM.

规格	价格	库存
10 mg	￥1180	In stock
25 mg	￥1980	In stock
50 mg	￥3480	In stock
100 mg		Get quote

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生物&药学活性

SJ-172550 (SJ172550) is the first small molecule MDMX inhibitor that reversibly binds the p53-binding pocket of MDMX, disrupts MDMX-p53 interaction with EC50 of 2.3 uM.

物理化学性质&存储条件

分子量	428.8655
分子式	C22H21ClN2O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Acetic acid, 2-[2-chloro-4-[(1,5-dihydro-3-methyl-5-oxo-1-phenyl-4H-pyrazol-4-ylidene)methyl]-6-ethoxyphenoxy]-, methyl ester

参考文献

1. Reed D, et al. J Biol Chem. 2010 Apr 2;285(14):10786-96.

2. Bista M, et al. PLoS One. 2012;7(6):e37518.

SJ-172550 (SJ172550;SJ 172550)

生物&药学活性

物理化学性质&存储条件

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SJ-172550 (SJ172550;SJ 172550)

生物&药学活性

物理化学性质&存储条件

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