SF0034 | Kv7.2/7.3 activator | Probechem Biochemicals

Chemical Structure : SF0034

加入收藏

SF0034 (SF-0034)

货号: PC-27791Not For Human Use, Lab Use Only.

SF0034 is a potent, sepcific KCNQ2/3 (Kv7.2/7.3) channel activator, shiftes the V1/2 of KCNQ2/3 currents with EC50 of 1.3 uM.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

SF0034 is a potent, sepcific KCNQ2/3 (Kv7.2/7.3) channel activator, shiftes the V1/2 of KCNQ2/3 currents with EC50 of 1.3 uM.
SF0034 is five times more potent than retigabine at shifting the voltage dependence of KCNQ2/3 channels to more negative voltages.
SF0034 does not shift the voltage dependence of either KCNQ4 or KCNQ5 homomeric channels.
SF0034 activates neuronal KCNQ2/3 channels and controls neuronal excitability.
SF0034 exhibits stronger anticonvulsant activity and is less toxic than retigabine.
SF0034 prevents the development of tinnitus.

物理化学性质&存储条件

分子量	321.33
分子式	C16H17F2N3O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	ethyl (2-amino-3-fluoro-4-((4-fluorobenzyl)amino)phenyl)carbamate

参考文献

1. Kalappa BI, et al. J Neurosci. 2015 Jun 10;35(23):8829-42.

SF0034 (SF-0034)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

SF0034 (SF-0034)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.