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首页-小分子抑制剂&激动剂-Others-Other Targets-SEN177
SEN177

Chemical Structure : SEN177

CAS No.: 2117405-13-5

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SEN177 (SEN-177)

货号: PC-49527Not For Human Use, Lab Use Only.

SEN177 (SEN-177) is a highly potent human glutaminyl cyclase (hQC) inhibitor Ki value of 20 nM.

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5 mg ￥880 In stock
10 mg ￥1280 In stock
25 mg ￥2180 In stock
50 mg ￥3480 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

SEN177 (SEN-177) is a highly potent human glutaminyl cyclase (hQC) inhibitor Ki value of 20 nM.
SEN177 demonstrated relevant pharmacological properties in in vivo models of Huntington's disease.

物理化学性质&存储条件

分子量 338.390
分子式 C18H19FN6
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

6'-fluoro-2-(4-(4-methyl-4H-1,2,4-triazol-3-yl)piperidin-1-yl)-3,3'-bipyridine

参考文献

1. Pozzi C, et al. J Biol Inorg Chem. 2018 Dec;23(8):1219-1226.

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