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首页-小分子抑制剂&激动剂-GPCR-Somatostatin Receptor-SCO-240
SCO-240

Chemical Structure : SCO-240

CAS No.: 1695564-98-7

SCO-240 (SCO240, SCO 240)

货号: PC-26763Not For Human Use, Lab Use Only.

SCO-240 is a potent, selective and oral somatostatin receptor subtype 5 (SSTR5) antagonist with IC50 of 2.0 nM (human SSTR5), >500-fold selectivity over other SSTR subtypes.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

SCO-240 is a potent, selective and oral somatostatin receptor subtype 5 (SSTR5) antagonist with IC50 of 2.0 nM (human SSTR5), >500-fold selectivity over other SSTR subtypes.

物理化学性质&存储条件

分子量 585.72
分子式 C35H40FN3O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

6-(1-((2-cyclopropyl-5-ethoxy-4'-fluoro-[1,1'-biphenyl]-4-yl)methyl)piperidin-4-yl)-5-oxo-2-propyl-5,6,7,8-tetrahydro-1,6-naphthyridine-3-carboxylic acid

参考文献

1. Nishizaki H, et al. Clin Pharmacol Ther. 2024 Jun;115(6):1326-1335.

2. Patent WO/2015/052910.

3. Nishizaki H, et al. Eur J Endocrinol. 2026 May 7:lvag081.

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