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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Cytochrome P450 (CYPs)-SCM-01
SCM-01

Chemical Structure : SCM-01

CAS No.: 380394-12-7

SCM-01

货号: PC-24395Not For Human Use, Lab Use Only.

SCM-01 is a potent, selective, non-suicide CYP3A4 inhibitor with IC50 of 0.32 uM in P450-Glo inhibition assays, 14-fold selecitve over CYP3A5.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

SCM-01 is a potent, selective, non-suicide CYP3A4 inhibitor with IC50 of 0.32 uM in P450-Glo inhibition assays, 14-fold selecitve over CYP3A5.

物理化学性质&存储条件

分子量 311.31
分子式 C15H16F3N3O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(2-(1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)pivalamide

参考文献

1. Jingheng Wang, et al. Nat Commun. 2025 Apr 10;16(1):3423.

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