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首页-小分子抑制剂&激动剂-GPCR-Prostaglandin Receptor-SC-51089
SC-51089

Chemical Structure : SC-51089

CAS No.: 146033-03-6

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SC-51089 (SC 51089, SC51089)

货号: PC-26606Not For Human Use, Lab Use Only.

SC-51089 (SC51089) is a selective antagonist of prostaglandin E2 EP1 receptor, with Ki values of 1.3, 11.2, 17.5, and 61.1 μM for EP1, TP, EP3, and FP receptors, respectively, exhibits neuroprotective activity.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

SC-51089 (SC51089) is a selective antagonist of prostaglandin E2 EP1 receptor, with Ki values of 1.3, 11.2, 17.5, and 61.1 μM for EP1, TP, EP3, and FP receptors, respectively, exhibits neuroprotective activity.

物理化学性质&存储条件

分子量 422.87
分子式 C22H19ClN4O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

8-Chloro-N'-(3-(pyridin-4-yl)propanoyl)dibenzo[b,f][1,4]oxazepine-10(11H)-carbohydrazide

参考文献

1. Lee K, et al. Xenobiotica. 1994 Jan;24(1):25-36.

2. Anglada-Huguet M, et, al. Mol Neurobiol. 2014 Apr;49(2):784-95.

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