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首页-小分子抑制剂&激动剂-Others-Other Targets-SB-633825
SB-633825

Chemical Structure : SB-633825

CAS No.: 956613-01-7

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SB-633825

货号: PC-25741Not For Human Use, Lab Use Only.

SB-633825 is a potent and ATP-competitive inhibitor of TIE2, LOK (STK10) and BRK with IC50s of 3.5 nM, 66 nM, 150 nM, respectively, inhibits cancer cell growth and angiogenesis.

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5 mg ￥1880 In stock
10 mg ￥2980 In stock
25 mg ￥4980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

SB-633825 is a potent and ATP-competitive inhibitor of TIE2, LOK (STK10) and BRK with IC50s of 3.5 nM, 66 nM, 150 nM, respectively, inhibits cancer cell growth and angiogenesis.

物理化学性质&存储条件

分子量 483.59
分子式 C28H25N3O3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-(5-(6-Methoxynaphthalen-2-yl)-1-methyl-2-(2-methyl-4-(methylsulfonyl)phenyl)-1H-imidazol-4-yl)pyridine

参考文献

1. Elkins JM, et al. Nat Biotechnol. 2016 Jan;34(1):95-103.

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