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首页-小分子抑制剂&激动剂-Cytoskeleton/Cell Adhesion Molecules-Microtubule/Tubulin-SB-216
SB-216

Chemical Structure : SB-216

CAS No.: 2756818-39-8

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SB-216 (SB216)

货号: PC-25918Not For Human Use, Lab Use Only.

SB-216 is a potent and brain-penetrable tubulin inhibitor, inhibits cell growth and migration, and induces apoptosis with low nanomolar potencies in breast cancer brain metastasis (BCBM) models.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

SB-216 is a potent and brain-penetrable tubulin inhibitor, inhibits cell growth and migration, and induces apoptosis with low nanomolar potencies in breast cancer brain metastasis (BCBM) models.

物理化学性质&存储条件

分子量 310.36
分子式 C17H18N4O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

7-Methoxy-4-(2-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)-3,4-dihydroquinoxalin-2(1H)-one

参考文献

1. Krutilina RI, et al. Mol Cancer Ther. 2025 Nov 24. doi: 10.1158/1535-7163.MCT-25-0538.

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