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首页-小分子抑制剂&激动剂-GPCR-Dopamine Receptor-S33084
S33084

Chemical Structure : S33084

CAS No.: 273203-30-8

S33084 (S-33084)

货号: PC-28317Not For Human Use, Lab Use Only.

S33084 is a potent, selective dopamine D3 receptor (D3R) antagonist with pKi of 9.2 (hD2), displays >100-fold selectivity over D4.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

S33084 is a potent, selective dopamine D3 receptor (D3R) antagonist with pKi of 9.2 (hD2), displays >100-fold selectivity over D4.

物理化学性质&存储条件

分子量 451.57
分子式 C29H29N3O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(4-((3aR,9bS)-8-cyano-1,3a,4,9b-tetrahydrochromeno[3,4-c]pyrrol-2(3H)-yl)butyl)-[1,1'-biphenyl]-4-carboxamide

参考文献

1. Millan MJ, et al. J Pharmacol Exp Ther. 2004 Jun;309(3):903-20.

2. Dubuffet T, et al. Bioorg Med Chem Lett. 1999 Jul 19;9(14):2059-64.

3. Cussac D, et al. Eur J Pharmacol. 2000 Apr 7;394(1):47-50.

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