S3226

首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Sodium Channel-S3226

Chemical Structure : S3226

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货号: PC-26525Not For Human Use, Lab Use Only.

S3226 is a potent, selective Na+/H+ exchanger subtype 3 (NHE3, SLC9A3) inhibitor with IC50 of 0.02 uM (hNHE3), shows >100-fold selectivity over hNHE1 and rbNHE2.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

S3226 is a potent, selective Na+/H+ exchanger subtype 3 (NHE3, SLC9A3) inhibitor with IC50 of 0.02 uM (hNHE3), shows >100-fold selectivity over hNHE1 and rbNHE2.

物理化学性质&存储条件

分子量	415.32
分子式	C17H24Cl2N6O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2E,2'E)-3,3'-(4-methyl-1,2-phenylene)bis(N-carbamimidoyl-2-methylacrylamide) dihydrochloride

参考文献

1. Schwark JR, et al. Pflugers Arch. 1998 Oct;436(5):797-800.

2. Wiemann M, et al. Pflugers Arch. 1999 Aug;438(3):255-62.

3. Hropot M, et al. Kidney Int. 2001 Dec;60(6):2283-9.

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S3226

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物理化学性质&存储条件

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S3226

生物&药学活性

物理化学性质&存储条件

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