Risuteganib (ALG-1001) | Integrin inhibitor | Probechem Biochemicals

Chemical Structure : Risuteganib

CAS No.: 1307293-62-4

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Risuteganib (ALG1001, ALG-1001)

货号: PC-35165Not For Human Use, Lab Use Only.

Risuteganib (ALG-1001) is a first-in-class, RGD class oligopeptide that inhibits integrin receptors (αvβ3, αvβ5, and α5β1) associated with angiogenesis.

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5 mg	￥1880	In stock
10 mg	￥2980	In stock
25 mg	￥4980	In stock
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生物&药学活性

Risuteganib (ALG-1001) is a first-in-class, RGD class oligopeptide that inhibits integrin receptors (αvβ3, αvβ5, and α5β1) associated with angiogenesis.
ALG1001 inhibits an integrin-mediated pathway of the vitreoretinal interface, connecting the posterior aspect of the vitreous with the internal limiting membrane of the retina.
In blocking this pathway, ALG-1001 helps to achieve vitreous breakdown and separation from the retina.

物理化学性质&存储条件

分子量	637.666
分子式	C22H39N9O11S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	L-Proline, glycyl-L-arginylglycyl-3-sulfo-L-alanyl-L-threonyl-

参考文献

1. Yang P, et al. Invest Ophthalmol Vis Sci. 2020 Aug 3;61(10):35.
2. Schneider K, et al. Exp Eye Res. 2021 Feb;203:108287.

Risuteganib (ALG1001, ALG-1001)

生物&药学活性

物理化学性质&存储条件

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Risuteganib (ALG1001, ALG-1001)

生物&药学活性

物理化学性质&存储条件

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