Rexipictor (VX-407) | Polycystin-1 corrector | Probechem Biochemicals

Chemical Structure : Rexipictor

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Rexipictor (VX-407, VX407)

货号: PC-27492Not For Human Use, Lab Use Only.

Rexipictor (VX-407) is a first-in-class small molecule Polycystin-1 (Polycystin 1, PC1, PKD1) corrector, corrects inappropriate PC1 folding to abate cystogenesis and eGFR decline, shows potential for treatment of autosomal dominant polycystic kidney disease (ADPKD).

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生物&药学活性

Rexipictor (VX-407) is a first-in-class small molecule Polycystin-1 (Polycystin 1, PC1, PKD1) corrector, corrects inappropriate PC1 folding to abate cystogenesis and eGFR decline, shows potential for treatment of autosomal dominant polycystic kidney disease (ADPKD).

物理化学性质&存储条件

分子量	471.89
分子式	C23H20ClF2N5O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4H-Pyrazolo[4,3-c]pyridin-4-one, 5-[5-chloro-2-[[(1S)-1-cyclopropyl-2-hydroxyethyl]amino]-4-pyridinyl]-1-[(2,6-difluorophenyl)methyl]-1,5-dihydro-

参考文献

1. Patent WO2025096453 A1 2025-05-08.

Rexipictor (VX-407, VX407)

生物&药学活性

物理化学性质&存储条件

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Rexipictor (VX-407, VX407)

生物&药学活性

物理化学性质&存储条件

参考文献

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