Chemical Structure : Reversine
CAS No.: 656820-32-5
货号: PC-21560Not For Human Use, Lab Use Only.
Reversine is a potent, ATP-competitive Aurora kinases inhibitor with IC50 of 400, 500 and 400 nM for Aurora A, Aurora B and Aurora C, respectively.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 10 mg | ¥580 | In stock | |
| 25 mg | ¥980 | In stock | |
| 50 mg | ¥1480 | In stock | |
| 100 mg | ¥2480 | In stock | |
| 250 mg | Get quote |
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Reversine is a potent, ATP-competitive Aurora kinases inhibitor with IC50 of 400, 500 and 400 nM for Aurora A, Aurora B and Aurora C, respectively.
Reversine promotes the dedifferentiation of committed cells into multipotent progenitor-type cells.
Reversine inhibited colony formation of leukemic cells from patients with acute myeloid leukemia.
| 分子量 | 393.50 | |
| 分子式 | C21H27N7O | |
| 外观性状 | Solid | |
| 储存条件 |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
N6-Cyclohexyl-N2-(4-morpholinophenyl)-9H-purine-2,6-diamine |
|
1. D'Alise AM, et al. Mol Cancer Ther. 2008 May;7(5):1140-9.
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