Chemical Structure : Relatlimab
CAS No.: 1673516-98-7
货号: PC-Ab1014Not For Human Use, Lab Use Only.
Relatlimab (BMS-986016) is a human IgG4 anti-LAG3 blocking mAb. Combination of LAG-3 with the immunomodulatory drug (IMiD) lenalidomide significantly increased IL-2 production by T cells and antibody-dependent cytotoxicity (ADCC) mediated by NK cells. These datas provide new insights into the potential anti-leukemic effects.
| 规格 | 价格 | 库存 | 数量 | 
|---|---|---|---|
| 1 mg | ¥3580 | In stock | |
| 5 mg | ¥7580 | In stock | |
| 10 mg | ¥12800 | In stock | |
| 100 mg | Get quote | 
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Relatlimab (BMS-986016) is a human IgG4 anti-LAG3 blocking mAb. Combination of LAG-3 with the immunomodulatory drug (IMiD) lenalidomide significantly increased IL-2 production by T cells and antibody-dependent cytotoxicity (ADCC) mediated by NK cells. These datas provide new insights into the potential anti-leukemic effects
| 分子量 | ||
| 分子式 | Human IgG4 (S228P)-Kappa | |
| 外观性状 | Solid | |
| 储存条件 | 
                            
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| Solubility | 
                             PBS, pH 7.0 Contains no stabilizers or preservatives  | 
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| Chemical Name/SMILES | 
                             Relatlimab; BMS-986016; 1673516-98-7; Anti-Lymphocyte Activation Gene 3; Lag3 protein; Anti-human lymphocyte activation 3 protein; Anti-human LAG-3; Anti-human CD223  | 
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1. 1, Christian Sordo-Bahamonde, et al. Cancers (Basel). 2021 Apr 27;13(9):2112. 2, Cancer Discov. 2021 Jul;11(7):1605-1606. 3, Yu X, et al. MAbs. 2019 Aug/Sep;11(6):1139-1148.
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