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首页-抗体和重组蛋白-Biosimilar Antibody-Ranibizumab
Ranibizumab

Chemical Structure : Ranibizumab

CAS No.: 347396-82-1

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Ranibizumab (Anti-human VEGFA mAb, human IgG1-Kappa; RG6321)

货号: PC-Ab1063Not For Human Use, Lab Use Only.

Ranibizumab (Lucentis, RG-6321) is a specific affinity-matured, recombinant, humanized, anti-VEGF antigen-binding antibody fragment (Fab) that binds and neutralizes all the biologically active forms of VEGF-A, an important mediator in the development of choroidal neovascularisation. Ranibizumab was approved by the Food and Drug Administration (FDA) for the treatment of neovascular AMD..

规格 价格 库存 数量
1 mg ￥3580 In stock
5 mg ￥7580 In stock
10 mg ￥12800 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Ranibizumab (Lucentis, RG-6321) is a specific affinity-matured, recombinant, humanized, anti-VEGF antigen-binding antibody fragment (Fab) that binds and neutralizes all the biologically active forms of VEGF-A, an important mediator in the development of choroidal neovascularisation. Ranibizumab was approved by the Food and Drug Administration (FDA) for the treatment of neovascular AMD.

物理化学性质&存储条件

分子量
分子式 Human IgG1-Kappa
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives
Chemical Name/SMILES

Ranibizumab; Lucentis; 347396-82-1; RG6321; RG-6321; vascular endothelial growth factor A; VEGFA Fab antibody.

参考文献

1. 1, Rosenfeld PJ, et al. N Engl J Med. 2006 Oct 5;355(14):1419-31. 2, Brown DM, et al. N Engl J Med. 2006 Oct 5;355(14):1432-44. 3, Ferrara N, et al. Retina. 2006 Oct;26(8):859-70. 4, Bakri SJ, et al. Am J Ophthalmol. 2007 Mar;143(3):505-7. 5, Gaudreault J, et al. Invest Ophthalmol Vis Sci. 2005 Feb;46(2):726-33.

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