RXR agonist V-125

Chemical Structure : RXR agonist V-125

CAS No.: 1807740-94-8

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货号: PC-26026Not For Human Use, Lab Use Only.

RXR agonist V-125 is a potent, selective next-generation RXR agonist with EC50 of 14 nM (RXRα activation).

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10 mg	￥780	In stock
25 mg	￥1280	In stock
50 mg	￥1980	In stock
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生物&药学活性

RXR agonist V-125 is a potent, selective next-generation RXR agonist with EC50 of 14 nM (RXRα activation).
V-125 reduces lung tumor burden in A/J mice.
V-125 delays the development of HER2-positive mammary tumors in MMTV-Neu mice.
V-125 alters immune-related biomarkers in MMTV-Neu tumors.
V-125 differentially regulates cancer-associated genes in tumors.

物理化学性质&存储条件

分子量	366.51
分子式	C23H30N2O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	6-(ethyl(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)amino)nicotinic acid

参考文献

1. Reich LA, et al. Sci Rep. 2022 Jan 7;12(1):293.

RXR agonist V-125

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物理化学性质&存储条件

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RXR agonist V-125

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物理化学性质&存储条件

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