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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Potassium Channel-RU-TRAAK-2
RU-TRAAK-2

Chemical Structure : RU-TRAAK-2

CAS No.: 1210538-56-9

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RU-TRAAK-2

货号: PC-70312Not For Human Use, Lab Use Only.

RU-TRAAK-2 is a completely reversible K2P channel TRAAK (KCNK4, K2P4.1) inhibitor with IC50 of 0.719 uM for TRAAK-mediated efflux, shows no activity for non-K2P channels (Kv1.2, Slo1 and GIRK2).

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5 mg ￥980 In stock
10 mg ￥1480 In stock
25 mg ￥2580 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

RU-TRAAK-2 is a completely reversible K2P channel TRAAK (KCNK4, K2P4.1) inhibitor with IC50 of 0.719 uM for TRAAK-mediated efflux, shows no activity for non-K2P channels (Kv1.2, Slo1 and GIRK2).

物理化学性质&存储条件

分子量 335.425
分子式 C19H17N3OS
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-(benzo[d]thiazol-2-ylmethyl)-1-methyl-3-(3-phenylprop-2-yn-1-yl)urea

参考文献

1. Su Z, et al. Proc Natl Acad Sci U S A. 2016 May 17;113(20):5748-53.

2. Cancer Res. 2017 Aug 15;77(16):4293-4304.

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