RP-54745 | IL-1 Inhibitor | Probechem Biochemicals

Chemical Structure : RP-54745

CAS No.: 135330-08-4

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RP-54745 (RP 54745, RP54745 )

货号: PC-24063Not For Human Use, Lab Use Only.

RP-54745 is a potential antirheumatic compound and interleukin-1 (IL-1) inhibitor, inhibits LPS-induced IL-1 production by murine peritoneal macrophages.

规格	价格	库存
5 mg	￥1280	In stock
10 mg	￥1980	In stock
25 mg	￥3580	In stock
50 mg	￥5580	In stock
100 mg		Get quote

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生物&药学活性

RP-54745 is a potential antirheumatic compound and interleukin-1 (IL-1) inhibitor, inhibits LPS-induced IL-1 production by murine peritoneal macrophages.
RP-54745 effectively repressed KSHV + PEL cell growth through inducing tumor cell apoptosis.
RP-54745 significantly reduced hyperinflammation in tumor microenvironment including myeloid cells and neutrophils infiltration, as well as blocking IL-1 signaling molecules expression in primary effusion lymphoma (PEL) xenograft model.

物理化学性质&存储条件

分子量	297.82
分子式	C13H12ClNOS2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-Chloro-5-(1-methyl-3,4-dihydroisoquinolin-2(1H)-yl)-3H-1,2-dithiol-3-one

参考文献

1. Folliard F, et al. Agents Actions. 1992 May;36(1-2):119-26.

2. Dai L, et al. J Med Virol. 2025 Feb;97(2):e70200.

RP-54745 (RP 54745, RP54745 )

生物&药学活性

物理化学性质&存储条件

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RP-54745 (RP 54745, RP54745 )

生物&药学活性

物理化学性质&存储条件

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