RL648_81 (RL648-81, RL-81)

Chemical Structure : RL648_81

CAS No.: 1919050-87-5

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货号: PC-27789Not For Human Use, Lab Use Only.

RL648_81 (RL648-81, RL-81) is a potent subtype-selective KCNQ2/3 (Kv7.2/7.3) channel activator with EC50 of 190 nM, >15 times more potent and also more selective than retigabine.

规格	价格	库存
10 mg	￥880	In stock
25 mg	￥1380	In stock
50 mg	￥2280	In stock
100 mg		Get quote

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生物&药学活性

RL648_81 (RL648-81, RL-81) is a potent subtype-selective KCNQ2/3 (Kv7.2/7.3) channel activator with EC50 of 190 nM, >15 times more potent and also more selective than retigabine.

物理化学性质&存储条件

分子量	371.34
分子式	C17H17F4N3O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Ethyl (2-amino-3-fluoro-4-((4-(trifluoromethyl)benzyl)amino)phenyl)carbamate

参考文献

1. Manoj Kumar, et al. Mol Pharmacol. 2016 Jun;89(6):667-77.