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首页-小分子抑制剂&激动剂-Apoptosis-Receptor Interacting Protein Kinase (RIPK)-RIPK2 inhibitor 1
RIPK2 inhibitor 1

Chemical Structure : RIPK2 inhibitor 1

CAS No.: 1290490-78-6

RIPK2 inhibitor 1 (FCG806791773, RIPK2-IN-3)

货号: PC-63258Not For Human Use, Lab Use Only.

RIPK2 inhibitor 1 (FCG806791773, RIPK2-IN-3) is a novel potent, selective RIPK2 inhibitor with IC50 of 5-10 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    RIPK2 inhibitor 1 (FCG806791773, RIPK2-IN-3) is a novel potent, selective RIPK2 inhibitor with IC50 of 5-10 nM.
    RIPK2 inhibitor 1 potently inhibits the proliferation of cancer cells by > 70% and also inhibits NF-κB activity.

    物理化学性质&存储条件

    分子量 410.477
    分子式 C25H22N4O2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    3-benzamido-4-methyl-N-[3-(1-methyl-1H-imidazol-2yl)phenyl]benzamide

    参考文献

    1. Salla M, et al. J Pharmacol Exp Ther. 2018 May;365(2):354-367.

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