RIG012 | RIG-I inhibitor | Probechem Biochemicals

Chemical Structure : RIG012

CAS No.: 2642218-43-5

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RIG012 (RIG-012)

货号: PC-26672Not For Human Use, Lab Use Only.

RIG012 (RIG-012) is a potent small molecule RIG-I receptor inhibitor/antagonist with IC50 of 0.71 uM in NADH-coupled ATPase assays, inhibits RIG-I signaling and interferon response in living cells.

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5 mg	￥880	In stock
10 mg	￥1280	In stock
25 mg	￥2180	In stock
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100 mg		Get quote

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生物&药学活性

RIG012 (RIG-012) is a potent small molecule RIG-I receptor inhibitor/antagonist with IC50 of 0.71 uM in NADH-coupled ATPase assays, inhibits RIG-I signaling and interferon response in living cells.

物理化学性质&存储条件

分子量	359.43
分子式	C23H21NO3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(Benzyloxy)-3,3-diethyl-2H-benzo[g]indole-2,5(3H)-dione

参考文献

1. David C Rawling, et al. Small-Molecule Antagonists of the RIG-I Innate Immune Receptor. ACS Chem Biol. 2020 Feb 21;15(2):311-317.

RIG012 (RIG-012)

生物&药学活性

物理化学性质&存储条件

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RIG012 (RIG-012)

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物理化学性质&存储条件

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