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首页-小分子抑制剂&激动剂-Immunology/Inflammation-RIG-I-like Receptor (RLR)-RIG-I agonist 95
RIG-I agonist 95

Chemical Structure : RIG-I agonist 95

CAS No.: 3072735-12-4

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RIG-I agonist 95

货号: PC-28668Not For Human Use, Lab Use Only.

RIG-I agonist 95 is a potent, direct-acting small-molecule RIG-I agonist, shows SPR KD of 9.5 uM for full-length RIG-I, activates the RIG-I pathway with high specificity and low cytotoxicity, selectively activates IFNs and ISGs in cellulo.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

RIG-I agonist 95 is a potent, direct-acting small-molecule RIG-I agonist, shows SPR KD of 9.5 uM for full-length RIG-I, activates the RIG-I pathway with high specificity and low cytotoxicity, selectively activates IFNs and ISGs in cellulo.

物理化学性质&存储条件

分子量 441.31
分子式 C23H18Cl2N2O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-((3,4-dichlorophenyl)(phenyl)methyl)-2,5-dioxo-1,2,5,6,7,8-hexahydroquinoline-3-carboxamide

参考文献

1. Guo R, et al. Nat Commun. 2026 Oct 19;17(1):10366.

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