RES-701-3

Chemical Structure : RES-701-3

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货号: PC-24438Not For Human Use, Lab Use Only.

RES-701-3 is a potent, selective antagonist of endothelin type B receptor (ETB receptor) with IC50 of 31.5 nM, with no activity against ETA. RES-701-3 functions as an inverse agonist.

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生物&药学活性

RES-701-3 is a potent, selective antagonist of endothelin type B receptor (ETB receptor) with IC50 of 31.5 nM, with no activity against ETA. RES-701-3 functions as an inverse agonist.

物理化学性质&存储条件

分子量	2059.2
分子式	C103H115N23O24
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N(1)Gly-DL-Asn-DL-Trp-DL-His-Gly-DL-Thr-DL-Ser-DL-Pro-DL-Asp(1)-DL-Trp-DL-Phe-DL-Phe-DL-Asn-DL-Tyr-DL-Tyr-DL-Trp-OH

参考文献

1. Pagotto U, et al. J Clin Invest. 1995 Oct;96(4):2017-25.

2. Hay DW, et al. Br J Pharmacol. 1996 Jul;118(5):1209-17.

3. Ogawa, T. et al. J. Antibiot. 48, 1213–1220 (1995).

4. Shihoya W, et al. Nat Commun. 2025 Apr 22;16(1):3446.

RES-701-3

生物&药学活性

物理化学性质&存储条件

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RES-701-3

生物&药学活性

物理化学性质&存储条件

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